Ascendia Pharmaceuticals offer service "AmorSol®"
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AmorSol®
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- Bioavailability Enhancement: AmorSol amorphous solid dispersion technology increases the apparent solubility and dissolution rate of poorly water-soluble (BCS Class II/IV) actives, improving oral bioavailability.
- Stability Indication: Formulations are engineered and screened for physical stability of the amorphous state (resistance to recrystallization) under long-term and accelerated storage conditions.
- Dosage Form: Amorphous solid dispersions are produced as intermediate powders suitable for downstream processing into capsules, tablets, or oral suspensions.
- Scale Capability: The spray-drying and hot-melt extrusion processes used to generate the dispersions are scalable from early feasibility batches to commercial manufacturing volumes.
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