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Chengdu Shengnuo Biopharm Co Ltd sell "Icatibant"

Basic Information

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Trade Type

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Product Name

Icatibant

Substance

Specifications

  • CAS Number: 130308-48-4
  • Chemical Formula: C59H89N19O13S
  • Formulation Type: Synthetic peptidomimetic decapeptide (ten amino acids)
  • IUPAC Name: (2S)-2-[[(2S,3aS,7aS)-1-[(3R)-2-[(2S)-2-[[(2S)-2-[[2-[[(2S,4R)-1-[(2S)-1-[(2S)-2-[[(2R)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]-4-hydroxypyrrolidine-2-carbonyl]amino]acetyl]amino]-3-
  • EC Number:
  • Molecular Weight: 1304.5
  • Regulatory Status: Approved in the EU for hereditary angioedema; holds US orphan drug status, FDA-approved August 25, 2011
  • Application: Specific bradykinin B2 receptor antagonist for treating hereditary angioedema and investigated for other bradykinin-mediated conditions

Other Information

Additional Description:

A synthetic, ten-amino-acid peptidomimetic drug acting as an effective, specific bradykinin B2 receptor antagonist, approved in the EU for hereditary angioedema and under investigation for other conditions where bradykinin plays a significant role. It holds orphan drug status in the US and received FDA approval on August 25, 2011, for HAE (hereditary angioedema).
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