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Jiangxi Alpha Hi-tech Pharmaceutical Co., Ltd. sell "Chlorobutanol Hemihydrate"

Basic Information

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Trade Type

Sell

Product Name

Chlorobutanol Hemihydrate

Specifications

  • CAS Number: 6001-64-5
  • Chemical Formula: C8H16Cl6O3
  • Solubility: Dissolves in ethanol, chloroform, ether, or volatile oils; sparingly soluble in water
  • IUPAC Name: bis(1,1,1-trichloro-2-methylpropan-2-ol);hydrate
  • EC Number: 611-927-0
  • Molecular Weight: 372.9
  • Functionality Test: Grades per CP2020/USP43-NF38/EP/BP/JP; the AG0402 hemihydrate grade specifically offers low related substances, low residual solvents, and low endotoxin control
  • Compatibility: Compatible with common tablet/capsule/topical excipients and active ingredients per standard formulation compatibility studies

Other Information

Additional Description:

Appearing as a white crystalline powder with a camphor-like odor that readily sublimes, this chlorobutanol hemihydrate dissolves in ethanol, chloroform, ether, or volatile oils but only slightly in water, meeting CP2020, USP43-NF38, EP9.0/10.0, BP2017/2020, and JP17 specifications. Commonly used as a preservative at around 0.5% w/v, it appears in ointments, ophthalmic preparations, and veterinary injections (such as oxytocin, colistin sulfate, chlorogenic acid, cephalexin, and tolfenamic acid), and is especially suited to non-aqueous preparations; it is bacteriostatic (not bactericidal) against Gram-positive and Gram-negative bacteria and some fungi like Candida albicans and Pseudomonas aeruginosa, though its activity drops markedly above pH 5.5.
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