Neopharmed Gentili S.p.A. sell "Antrolin"
Basic Information
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Sell
Product Name
Antrolin
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Specifications
- Content Uniformity: Content uniformity is tested batch-to-batch to confirm consistent active ingredient dosing, per pharmacopeial requirements.
- Container Closure Integrity: Container closure integrity is validated to protect the product from contamination and ensure stability through shelf life.
- Particulate Matter: Particulate matter is tested and controlled within pharmacopeial limits appropriate to the dosage form.
Other Information
Additional Description:
A nifedipine plus lidocaine hydrochloride cream for rectal application, indicated for anal fissure and proctalgia typically linked to anal sphincter hypertonia. Nifedipine blocks calcium ion flow into the anal sphincter's smooth muscle, acting as a muscle relaxant, anti-inflammatory, and microcirculation regulator, while lidocaine blocks pain signal transmission for an analgesic effect. Antrolin has shown a synergistic mechanism between nifedipine and lidocaine, clinical remission of thrombosed hemorrhoids, pain relief after hemorrhoidectomy, effective healing of anal fissures, and good tolerability even on injured anorectal mucosa.
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