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Basic Information

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Trade Type

Sell

Product Name

Larotrectinib

Substance

Specifications

  • EC Number: 826-190-2
  • CAS Number: 1223403-58-4
  • IUPAC Name: (3S)-N-[5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidin-3-yl]-3-hydroxypyrrolidine-1-carboxamide
  • Application: Oral TRK (tropomyosin receptor kinase) inhibitor for Trk-positive solid tumors
  • Molecular Weight: 428.4
  • Chemical Formula: C21H22F2N6O2
  • Regulatory Status: FDA accelerated approval (November 2018); tissue-agnostic indication

Documents

US FDA
FDA audit approved and EDQM approved
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