Title Cited by Year A potent and selective small-molecule degrader of STAT3 achieves complete tumor regression in vivo L Bai, H Zhou, R Xu, Y Zhao, K Chinnaswamy, D McEachern, J Chen, ... Cancer cell 36 (5), 498-511. e17 554 2019 Structure-based discovery of SD-36 as a potent, selective, and efficacious PROTAC degrader of STAT3 protein H Zhou, L Bai, R Xu, Y Zhao, J Chen, D McEachern, K Chinnaswamy, ... Journal of medicinal chemistry 62 (24), 11280-11300 190 2019 Structure-based design of high-affinity macrocyclic peptidomimetics to block the menin-mixed lineage leukemia 1 (MLL1) protein–protein interaction H Zhou, L Liu, J Huang, D Bernard, H Karatas, A Navarro, M Lei, S Wang Journal of Medicinal Chemistry 56 (3), 1113-1123 111 2013 BM-1197: a novel and specific Bcl-2/Bcl-xL inhibitor inducing complete and long-lasting tumor regression in vivo L Bai, J Chen, D McEachern, L Liu, H Zhou, A Aguilar, S Wang PloS one 9 (6), e99404 110 2014 Short and efficient total synthesis of luotonin A and 22-hydroxyacuminatine using a common cascade strategy HB Zhou, GS Liu, ZJ Yao The Journal of Organic Chemistry 72 (16), 6270-6272 102 2007 Design of Bcl-2 and Bcl-xL inhibitors with subnanomolar binding affinities based upon a new scaffold H Zhou, J Chen, JL Meagher, CY Yang, A Aguilar, L Liu, L Bai, X Cong, ... Journal of medicinal chemistry 55 (10), 4664-4682 101 2012 A potent small-molecule inhibitor of the DCN1-UBC12 interaction that selectively blocks cullin 3 neddylation H Zhou, J Lu, L Liu, D Bernard, CY Yang, E Fernandez-Salas, ... Nature communications 8 (1), 1150 92 2017 Highly efficient and mild cascade reactions triggered by bis (triphenyl) oxodiphosphonium trifluoromethanesulfonate and a concise total synthesis of camptothecin HB Zhou, GS Liu, ZJ Yao Organic Letters 9 (10), 2003-2006 91 2007 Structure-based design of potent Bcl-2/Bcl-xL inhibitors with strong in vivo antitumor activity H Zhou, A Aguilar, J Chen, L Bai, L Liu, JL Meagher, CY Yang, ... Journal of medicinal chemistry 55 (13), 6149-6161 79 2012 Structure-based discovery of BM-957 as a potent small-molecule inhibitor of Bcl-2 and Bcl-xL capable of achieving complete tumor regression J Chen, H Zhou, A Aguilar, L Liu, L Bai, D McEachern, CY Yang, ... Journal of medicinal chemistry 55 (19), 8502-8514 71 2012 A potent and highly efficacious Bcl-2/Bcl-xL inhibitor A Aguilar, H Zhou, J Chen, L Liu, L Bai, D McEachern, CY Yang, ... Journal of medicinal chemistry 56 (7), 3048-3067 69 2013 High-affinity peptidomimetic inhibitors of the DCN1-UBC12 protein–protein interaction H Zhou, W Zhou, B Zhou, L Liu, TR Chern, K Chinnaswamy, J Lu, ... Journal of Medicinal Chemistry 61 (5), 1934-1950 60 2018 Cullin 4B protein ubiquitin ligase targets peroxiredoxin III for degradation X Li, D Lu, F He, H Zhou, Q Liu, Y Wang, C Shao, Y Gong Journal of Biological Chemistry 286 (37), 32344-32354 58 2011 Resveratrol sequentially induces replication and oxidative stresses to drive p53-CXCR2 mediated cellular senescence in cancer cells B Li, D Hou, H Guo, H Zhou, S Zhang, X Xu, Q Liu, X Zhang, Y Zou, ... Scientific reports 7 (1), 208 52 2017 MicroRNA-26a-5p and microRNA-23b-3p up-regulate peroxiredoxin III in acute myeloid leukemia W Jiang, J Min, X Sui, Y Qian, Y Liu, Z Liu, H Zhou, X Li, Y Gong Leukemia & lymphoma 56 (2), 460-471 51 2015 Bcl-2/Bcl-xL inhibitors and therapeutic methods using the same S Wang, H Zhou, J Chen, A Aguilar, JL Meagher, D Sun, CY Yang, L Liu, ... US Patent 8,691,184 45 2014 Metal-free synthesis of alkynyl imines using an oxophosphonium-mediated approach at ambient temperatures QL Dong, GS Liu, HB Zhou, L Chen, ZJ Yao Tetrahedron Letters 49 (10), 1636-1640 45 2008 SD-91 as a potent and selective STAT3 degrader capable of achieving complete and long-lasting tumor regression H Zhou, L Bai, R Xu, D McEachern, K Chinnaswamy, R Li, B Wen, ... ACS Medicinal Chemistry Letters 12 (6), 996-1004 38 2021 Selective inhibition of cullin 3 neddylation through covalent targeting DCN1 protects mice from acetaminophen-induced liver toxicity