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American software company founded in 2000 at Columbus in Ohio out of work at the Ohio State University, bought by the British group Instem in 2014 and now part of its in silico and computational toxicology business. Makes software and databases for predictive toxicology, with structure searching and data mining of chemical and toxicity data, statistical and expert quantitative structure activity relationship models for genotoxicity, carcinogenicity and impurity assessment used for regulatory submissions under the ICH M7 guideline, and the toxicity databases behind them.
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